Search on: PYRIMIDINE DIMERS 
Descriptors Found: 1
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Descriptor English:   Pyrimidine Dimers 
Descriptor Spanish:   Dímeros de Pirimidina 
Descriptor Portuguese:   Dímeros de Pirimidina 
Synonyms English:   Cyclobutane Dimer, Thymine-Thymine
Cyclobutane Pyrimidine Dimers
Cyclobutane-Pyrimidine Dimers
Cytosine Thymine Dimers
Cytosine-Thymine Dimers
Dimer, Thymine-Cyclobutane
Dimer, Thymine-Thymine Cyclobutane
Dimers, Cyclobutane-Pyrimidine
Dimers, Cytosine-Thymine
Dimers, Pyrimidine
Dimers, Thymine
Thymine Cyclobutane Dimer
Thymine Dimers
Thymine Thymine Cyclobutane Dimer
Thymine-Cyclobutane Dimer
Thymine-Thymine Cyclobutane Dimer  
Tree Number:   D03.383.742.686.600
D13.695.578.424.600
D13.695.740.600
Definition English:   Dimers found in DNA chains damaged by ULTRAVIOLET RAYS. They consist of two adjacent PYRIMIDINE NUCLEOTIDES, usually THYMINE nucleotides, in which the pyrimidine residues are covalently joined by a cyclobutane ring. These dimers block DNA REPLICATION. 
See Related English:   DNA Damage
 
History Note English:   77 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   12177 
Unique Identifier:   D011740 

Occurrence in VHL: 		 

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